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Catalog No. BCC4169
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Quality Control of (R)-Oxiracetam

Chemical structure


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Chemical Properties of (R)-Oxiracetam

Cas No. 68252-28-8 SDF Download SDF
Chemical Name 2-[(4R)-4-hydroxy-2-oxopyrrolidin-1-yl]acetamide
Standard InChI InChI=1S/C6H10N2O3/c7-5(10)3-8-2-4(9)1-6(8)11/h4,9H,1-3H2,(H2,7,10)/t4-/m1/s1
Formula C6H10N2O3 M.Wt 158.16
Solubility Soluble in DMSO
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of (R)-Oxiracetam

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.3227 mL 31.6136 mL 63.2271 mL 126.4542 mL 158.0678 mL
5 mM 1.2645 mL 6.3227 mL 12.6454 mL 25.2908 mL 31.6136 mL
10 mM 0.6323 mL 3.1614 mL 6.3227 mL 12.6454 mL 15.8068 mL
50 mM 0.1265 mL 0.6323 mL 1.2645 mL 2.5291 mL 3.1614 mL
100 mM 0.0632 mL 0.3161 mL 0.6323 mL 1.2645 mL 1.5807 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Background on (R)-Oxiracetam

(R)-Oxiracetam is the (R)-enantiomer of the nootropic drug oxiracetam. Oxiracetam (ISF 2522) is a nootropic drug of the racetam family and stimulant.

References on (R)-Oxiracetam

Pharmacokinetic comparisons of S-oxiracetam and R-oxiracetam in beagle dogs.[Pubmed: 27279070]

A pharmacokinetic comparison and conformational stability study of S-oxiracetam (S-ORT) and R-oxiracetam (R-ORT) in beagle dogs was used to investigate the possible mechanism of different effects of two oxiracetam enantiomers through a random crossover design. After drug administration to beagle dogs, blood samples were collected at different time points for pharmacokinetic analysis using the UPLC-ESI-MS/MS method. Parts of plasma samples were used for conformation transformation studies using a normal phase high performance liquid chromatographic (NP HPLC) method. The study showed that oxiracetam enantiomers maintained their original conformation when administered orally to beagle dogs. Concentrations of S-ORT were significantly higher than R-ORT 1.5 and 2 h after administration; the AUC0-∞ of S-ORT after oral administration tended to be higher than that of R-ORT, which showed that the different effects between S-ORT and R-ORT may be partly associated with their distinctive absorption at least.


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