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[Orn8]-Urotensin II

[Orn8]-Urotensin II

Catalog No. BCC5793
Size Price Stock
1mg $225.00 Ship Within 7 Days
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Quality Control of [Orn8]-Urotensin II

Chemical structure

[Orn8]-Urotensin II

Biological Activity of [Orn8]-Urotensin II

Inhibitor of glycogen synthase kinase-3 (GSK-3); derived from FRAT1, the mammalian version of GSK-3-binding protein. Binds to GSK-3, inhibiting its interaction with axin, and also blocks GSK-3-catalyzed phosphorylation of axin and β-catenin. Does not affect GSK-3-mediated phosphorylation of glycogen synthase or eIF2B.

[Orn8]-Urotensin II Dilution Calculator

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[Orn8]-Urotensin II Molarity Calculator

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Chemical Properties of [Orn8]-Urotensin II

Cas No. 479065-85-5 SDF Download SDF
Chemical Name (4S)-4-amino-5-[[(2S,3R)-1-[(2S)-2-[[(2S)-1-[[(4R,7S,10S,13S,16S,19R)-10-(3-aminopropyl)-16-benzyl-4-[[(1S)-1-carboxy-2-methylpropyl]carbamoyl]-7-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicos-19-yl]amino]-3-carboxy-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
SMILES CC(C)C(C(=O)O)NC(=O)C1CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CC2=CC=C(C=C2)O)CCCN)CC3=CNC4=CC=CC=C43)CC5=CC=CC=C5)NC(=O)C(CC(=O)O)NC(=O)C6CCCN6C(=O)C(C(C)O)NC(=O)C(CCC(=O)O)N
Standard InChIKey KBCMJGTVVAXGOV-QXHQCLFZSA-N
Standard InChI InChI=1S/C63H83N13O18S2/c1-32(2)51(63(93)94)74-60(90)47-31-96-95-30-46(72-58(88)45(28-50(81)82)71-61(91)48-16-10-24-76(48)62(92)52(33(3)77)75-53(83)39(65)21-22-49(79)80)59(89)69-42(25-34-11-5-4-6-12-34)55(85)70-44(27-36-29-66-40-14-8-7-13-38(36)40)57(87)67-41(15-9-23-64)54(84)68-43(56(86)73-47)26-35-17-19-37(78)20-18-35/h4-8,11-14,17-20,29,32-33,39,41-48,51-52,66,77-78H,9-10,15-16,21-28,30-31,64-65H2,1-3H3,(H,67,87)(H,68,84)(H,69,89)(H,70,85)(H,71,91)(H,72,88)(H,73,86)(H,74,90)(H,75,83)(H,79,80)(H,81,82)(H,93,94)/t33-,39+,41+,42+,43+,44+,45+,46+,47+,48+,51+,52+/m1/s1
Formula C63H83N13O18S2 M.Wt 1374.54
Solubility Soluble to 100 mM in DMSO and to 100 mM in ethanol
Storage Desiccate at -20°C
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other courier with RT , or blue ice upon request.

Preparing Stock Solutions of [Orn8]-Urotensin II

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 0.7275 mL 3.6376 mL 7.2752 mL 14.5503 mL 18.1879 mL
5 mM 0.1455 mL 0.7275 mL 1.455 mL 2.9101 mL 3.6376 mL
10 mM 0.0728 mL 0.3638 mL 0.7275 mL 1.455 mL 1.8188 mL
50 mM 0.0146 mL 0.0728 mL 0.1455 mL 0.291 mL 0.3638 mL
100 mM 0.0073 mL 0.0364 mL 0.0728 mL 0.1455 mL 0.1819 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

Kewords:

[Orn8]-Urotensin II,479065-85-5,GPCR/G protein,Urotensin-II Receptor, supplier, inhibitor,Antagonist,Blocker,Modulator,Agonist, activators, activates, potent, BioCrick

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