Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 56

  1. Cat.No. Product Name Information/Activity
  2. BCC6572 Kainic acid Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. Kainic acid chemical structure
  3. BCC7297 MNI caged kainic acid 1315378-75-6 MNI caged kainic acid chemical structure
  4. BCC6840 SYM 2081 SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. SYM 2081 chemical structure
  5. BCC7462 ACET 936095-50-0 ACET chemical structure
  6. BCC7275 NS 3763 70553-45-6 NS 3763 chemical structure
  7. BCC7255 UBP 296 745055-86-1 UBP 296 chemical structure
  8. BCC7172 UBP 301 569371-10-4 UBP 301 chemical structure
  9. BCC7256 UBP 302 UBP 302 is a potent and selective GLUK5-subunit containing kainate receptor antagonist (apparent Kd=402 nM), and displays very little affinity on GluK2 (GluR6) kainate receptors. Anxiolytic effects. UBP 302 chemical structure
  10. BCC6052 UBP 310 902464-46-4 UBP 310 chemical structure
  11. BCN6291 Arctigenin Arctigenin is a lignan found in certain plants of the Asteraceae; it has shown antiviral and anticancer effects in glass; it is the aglycone of arctiin. Arctigenin chemical structure

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