Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 62

  1. Cat.No. Product Name Information/Activity
  2. BCC6755 L-701,252 151057-13-5 L-701,252 chemical structure
  3. BCC6842 L-701,324 L-701324 is an orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor. L-701,324 chemical structure
  4. BCC5771 LY 233053 125546-04-5 LY 233053 chemical structure
  5. BCC6892 LY 235959 137433-06-8 LY 235959 chemical structure
  6. BCC4593 (-)-MK 801 (-)-Dizocilpine maleate ((-)-MK-801 maleate) is a less active (-)-enantiomer of Dizocilpine. (-)-Dizocilpine maleate is a selective and non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist with a Ki of 211.7 nM. (-)-Dizocilpine maleate has antidepressant effects. (-)-MK 801 chemical structure
  7. BCC4014 (+)-MK 801 Maleate Dizocilpine maleate (MK-801 maleate) is a potent, selective and non-competitive NMDA receptor antagonist with Kd of 37.2 nM in rat brain membranes. (+)-MK 801 Maleate chemical structure
  8. BCC5859 Norketamine hydrochloride 79499-59-5 Norketamine hydrochloride chemical structure
  9. BCC7895 NPEC-caged-D-AP5 1416943-27-5 NPEC-caged-D-AP5 chemical structure
  10. BCC5644 Pentamidine isethionate Pentamidine isethionate (MP-601205 isethionate) is an antimicrobial agent and interferes with DNA biosynthetics. Pentamidine isethionate inhibits parasite Leishmania infantum with an IC50 of 2.5 μM. Pentamidine isethionate is a potent and selective protein tyrosine phosphatases (PTPases) and phosphatase of regenerating liver (PRL) inhibitor. Pentamidine isethionate has the potential for Gambian trypanosomiasis, antimony-resistant leishmaniasis, and Pneumocystis carinii pneumonia treatment. Antitumor and antibacterial activities. Pentamidine isethionate chemical structure
  11. BCC7308 PMPA (NMDA antagonist) 113919-36-1 PMPA (NMDA antagonist) chemical structure

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