Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 54

  1. Cat.No. Product Name Information/Activity
  2. BCC6759 Cyclothiazide 2259-96-3 Cyclothiazide chemical structure
  3. BCC5951 PEPA PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity. PEPA chemical structure
  4. BCC6322 PF 4778574 PF-4778574 is a positive allosteric modulation of AMPA receptor with EC50 of 45 to 919 nM in differenct cells. PF 4778574 chemical structure
  5. BCC6081 S 18986 S 18986 is a selective, orally active, brain penetrant positive allosteric modulator of AMPA-type receptors. S 18986 shows cognitive enhancing properties in rodents. S 18986 activates the release of noradrenaline and acetylcholine in rat hippocampus and enhances rat memory in object-recognition tests. S 18986 chemical structure
  6. BCC4219 Aniracetam Aniracetam(Ro 13-5057) is a nootropics and neuroprotective drug, which is selectively modulates the AMPA receptor and nAChR. Aniracetam chemical structure
  7. BCC6974 IDRA 21 22503-72-6 IDRA 21 chemical structure
  8. BCC5787 pep2-AVKI 1315378-69-8 pep2-AVKI chemical structure
  9. BCC5786 pep2-EVKI 1315378-67-6 pep2-EVKI chemical structure
  10. BCC5782 pep2m 243843-42-7 pep2m chemical structure
  11. BCC5784 pep2-SVKI 328944-75-8 pep2-SVKI chemical structure

Items 531 to 540 of 752 total