Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 57

  1. Cat.No. Product Name Information/Activity
  2. BCC5883 PDZ1 Domain inhibitor peptide 1315378-73-4 PDZ1 Domain inhibitor peptide chemical structure
  3. BCC6566 cis-ACPD 477331-06-9 cis-ACPD chemical structure
  4. BCC2894 H-D-Asp-OH (-)-Aspartic acid is an endogenous NMDA receptor agonist. H-D-Asp-OH chemical structure
  5. BCC2881 H-Asp-OH L-Aspartic acid is is an amino acid, shown to be a suitable prodrug for colon-specific drug deliverly. H-Asp-OH chemical structure
  6. BCC6571 L-Cysteinesulfinic acid L-Cysteinesulfinic acid is a potent agonist at several rat metabotropic glutamate receptors (mGluRs) with pEC50s of 3.92±0.03, 4.6±0.2, 3.9±0.2, 2.7±0.2, 4.0±0.2, and 3.94±0.08 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively. L-Cysteinesulfinic acid chemical structure
  7. BCC6013 GLYX 13 Rapastinel (GLYX-13) is an N-methyl-D-aspartate receptor (NMDAR) modulator that has characteristics of a glycine site partial agonist. GLYX 13 chemical structure
  8. BCC6588 (R)-(+)-HA-966 (R)-(+)-HA-966 ((+)-HA-966) is a partial agonist/antagonist of glycine site of the N-methyl-D-aspartate (NMDA) receptor complex. (R)-(+)-HA-966 selectively blocks the activation of the mesolimbic dopamine system by amphetamine. (R)-(+)-HA-966 can cross the blood-brain barrier and has the potential for neuropathic and acute pain. (R)-(+)-HA-966 chemical structure
  9. BCC6570 Homoquinolinic acid 490-75-5 Homoquinolinic acid chemical structure
  10. BCC6591 Ibotenic acid Ibotenic acid has agonist activity at both the N-methyl-D-aspartate (NMDA) and trans-ACPD or metabolotropic quisqualate (Qm) receptor sites. Ibotenic acid chemical structure
  11. BCC5896 MNI-caged-D-aspartate 845555-94-4 MNI-caged-D-aspartate chemical structure

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