Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 55

  1. Cat.No. Product Name Information/Activity
  2. BCC7135 IEM 1460 121034-89-7 IEM 1460 chemical structure
  3. BCC5049 IEM 1754 dihydrobroMide IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM. IEM 1754 dihydrobroMide chemical structure
  4. BCC6909 1-BCP 1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents. 1-BCP is a memory-enhancing agent. 1-BCP chemical structure
  5. BCC6868 Diazoxide Diazoxide (Sch-6783) is an ATP-sensitive potassium channel activator, has the potential for hyperinsulinism treatment. Diazoxide chemical structure
  6. BCC5785 pep2-SVKE 1315378-76-7 pep2-SVKE chemical structure
  7. BCC5783 pep4c 243843-43-8 pep4c chemical structure
  8. BCC4824 Piracetam Piracetam (UCB-6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders. Piracetam chemical structure
  9. BCC6940 ATPA ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively. ATPA chemical structure
  10. BCC6586 Domoic acid 14277-97-5 Domoic acid chemical structure
  11. BCC6597 (S)-(-)-5-Iodowillardiine 140187-25-3 (S)-(-)-5-Iodowillardiine chemical structure

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