Catechol O-Methyltransferase
Catechol O-Methyltransferase (COMT) (EC 2.1.1.6) catalyzes the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to a catechol substrate, such as dopamine or levodopa, in the presence of magnesium (Mg2+) ions.
Products for Catechol O-Methyltransferase
- Cat.No. Product Name Information/Activity
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BCC2217
Entacapone
Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment.
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BCC5661
OR-486
7659-29-2
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BCC2334
Tolcapone
COMT inhibitor; also inhibits transthyretin aggregation,Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.
