Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 64

  1. Cat.No. Product Name Information/Activity
  2. BCC6730 Synthalin sulfate 182285-12-7 Synthalin sulfate chemical structure
  3. BCC6122 TCN 201 852918-02-6 TCN 201 chemical structure
  4. BCC6123 TCN 213 556803-08-8 TCN 213 chemical structure
  5. BCC6111 TCN 237 dihydrochloride NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor. TCN 237 dihydrochloride chemical structure
  6. BCC7482 TCS 46b 302799-86-6 TCS 46b chemical structure
  7. BCC6984 CCMQ 132623-44-0 CCMQ chemical structure
  8. BCC7862 CIQ CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. CIQ chemical structure
  9. BCC2946 H-Gly-OH Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors. H-Gly-OH chemical structure
  10. BCC5888 MNI-caged-NMDA 1227675-52-6 MNI-caged-NMDA chemical structure
  11. BCC7292 N20C hydrochloride 1177583-87-7 N20C hydrochloride chemical structure

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