Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 36

  1. Cat.No. Product Name Information/Activity
  2. BCC6644 ML 9 hydrochloride ML-9 is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity. ML-9 inhibits inhibits MLCK, PKA and PKC activity with Ki values of 4, 32 and 54 μM, respectively. ML-9 induces autophagy by stimulating autophagosome formation and inhibiting their degradation. ML 9 hydrochloride chemical structure
  3. BCC6953 SKF 96365 hydrochloride SKF-96365 hydrochloride is a non-selective TRP Channel blocker. SKF 96365 hydrochloride chemical structure
  4. BCC7817 YM 58483 YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals. YM 58483 chemical structure
  5. BCC3918 (±)-Bay K 8644 Ca<sup>2+</sup> channel activator (L-type); aids generation of iPSCs from MEFs (±)-Bay K 8644 chemical structure
  6. BCC7108 (S)-(-)-Bay K 8644 (S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel. (S)-(-)-Bay-K-8644 activates Ba2+ currents (IBa) (EC50=32 nM). (S)-(-)-Bay K 8644 chemical structure
  7. BCC7050 FPL 64176 120934-96-5 FPL 64176 chemical structure
  8. BCC4504 Nefiracetam Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions. Nefiracetam chemical structure
  9. BCC7488 ω-Agatoxin IVA 145017-83-0 ω-Agatoxin IVA chemical structure
  10. BCC7489 ω-Agatoxin TK 158484-42-5 ω-Agatoxin TK chemical structure
  11. BCC4397 Amlodipine Besylate Amlodipine besylate is a long-acting calcium channel blocker. Amlodipine Besylate chemical structure

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