Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 50

  1. Cat.No. Product Name Information/Activity
  2. BCC6550 L-AP4 L-APB is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively. L-AP4 chemical structure
  3. BCC7865 Cinnabarinic acid 606-59-7 Cinnabarinic acid chemical structure
  4. BCC7045 (RS)-3,4-DCPG 176796-64-8 (RS)-3,4-DCPG chemical structure
  5. BCC7012 (S)-3,4-DCPG 201730-11-2 (S)-3,4-DCPG chemical structure
  6. BCC7652 NPEC-caged-(S)-3,4-DCPG 1257323-85-5 NPEC-caged-(S)-3,4-DCPG chemical structure
  7. BCC6578 O-Phospho-L-serine O-Phospho-L-serine is the immediate precursor to L-serine in the serine synthesis pathway, and an agonist at the group III mGluR receptors (mGluR4, mGluR6, mGluR7, and mGluR8); O-Phospho-L-serine also acts as a weak antagonist for mGluR1 and a potent antagonist for mGluR2. O-Phospho-L-serine chemical structure
  8. BCC6975 (RS)-PPG (RS)-PPG is a potent and selective agonist for group III mGluRs. The EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively. Anticonvulsive and neuroprotective activity. (RS)-PPG chemical structure
  9. BCC7615 VU 0155041 1093757-42-6 VU 0155041 chemical structure
  10. BCC7642 VU 0155041 sodium salt 1259372-69-4 VU 0155041 sodium salt chemical structure
  11. BCC7616 Z-Cyclopentyl-AP4 103439-17-4 Z-Cyclopentyl-AP4 chemical structure

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