Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 48

  1. Cat.No. Product Name Information/Activity
  2. BCC7368 LY 379268 Highly selective group II mGlu agonist LY 379268 chemical structure
  3. BCC7623 (±)-LY 395756 852679-66-4 (±)-LY 395756 chemical structure
  4. BCC6758 MAP4 157381-42-5 MAP4 chemical structure
  5. BCC6925 (RS)-APICA 170847-18-4 (RS)-APICA chemical structure
  6. BCC6871 EGLU EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent. EGLU chemical structure
  7. BCC1724 LY341495 LY341495 is a metabotropic glutamate receptor (mGluR) antagonist with IC50s of 2.9 nM, 10 nM, 170 nM for mGluR-2, mGluR-3, mGluR-8, respectively. LY341495 chemical structure
  8. BCC6819 MSPG 169209-64-7 MSPG chemical structure
  9. BCC6820 MTPG 169209-66-9 MTPG chemical structure
  10. BCC7513 Ro 64-5229 246852-46-0 Ro 64-5229 chemical structure
  11. BCC7849 BINA Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders. BINA chemical structure

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