Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 57

  1. Cat.No. Product Name Information/Activity
  2. BCC6845 3-CPMT 14008-79-8 3-CPMT chemical structure
  3. BCC6676 GBR 12783 dihydrochloride GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor that inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively. GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats. GBR 12783 dihydrochloride chemical structure
  4. BCC5129 Vanoxerine dihydrochloride Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM). Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) binds to the target site on the dopamine transporter (DAT). Vanoxerine dihydrochloride chemical structure
  5. BCC5380 GBR 12935 dihydrochloride GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor. GBR 12935 dihydrochloride chemical structure
  6. BCC6640 GBR 13069 dihydrochloride 67469-45-8 GBR 13069 dihydrochloride chemical structure
  7. BCC7923 JHW 007 hydrochloride 202645-74-7 JHW 007 hydrochloride chemical structure
  8. BCN4960 Reserpine Evacetrapib is a potent and selective of CETP inhibitor, which inhibits human recombinant CETP protein (IC50 5.5 nM) and CETP activity in human plasma (IC50 36 nM) in vitro. Reserpine chemical structure
  9. BCC7090 Rimcazole dihydrochloride 75859-03-9 Rimcazole dihydrochloride chemical structure
  10. BCC2851 H-ß-Ala-OH β-Alanine is a non-essential amino acid that is shown to be metabolized into carnosine, which functions as an intracellular buffer. H-ß-Ala-OH chemical structure
  11. BCC7010 CI 966 hydrochloride 110283-66-4 CI 966 hydrochloride chemical structure

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