Depression Research
Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.
Depression Research Products Targets
- FGFR (5)
- Voltage-gated Calcium Channel (CaV) (38)
- Others (13)
- Glucocorticoid Receptor (9)
- Nucleoside Transporter (5)
- Glycine Transporter (6)
- GABA (10)
- Cannabinoid Transporter (10)
- Acetylcholine Transporter (1)
- D4 Receptor (12)
- 5-HT7 Receptor (11)
- 5-HT6 Receptor (14)
- 5-ht5 Receptor (2)
- 5-HT4 Receptor (17)
- NK2 Receptor (7)
- NK1 Receptor (15)
- Glutamate (Metabotropic) Group III Receptor (26)
- Glutamate (Metabotropic) Group II Receptor (33)
- Glutamate (Metabotropic) Group I Receptor (54)
- AMPA Receptor (45)
- D3 Receptor (12)
- NK3 Receptor (5)
- Vesicular Monoamine Transporter (4)
- NMDA Receptor (87)
- Kainate Receptor (22)
- D2 Receptor (14)
- D1 and D5 Receptor (16)
- Trk Receptor (13)
- Trace Amine 1 Receptor (2)
- Glutamate Transporter (18)
- Dopamine Transporter (20)
- CRF2 Receptor (3)
- CRF1 Receptor (5)
- Adrenergic Transporter (23)
- 5-HT Transporter (30)
- Vasopressin Receptor (6)
- Monoamine Oxidase (10)
- Adrenergic α2 Receptor (33)
- Adrenergic α1 Receptor (22)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
Products for Depression Research - Page 53
- Cat.No. Product Name Information/Activity
-
BCC7123
Indatraline hydrochloride
96850-13-4
-
BCC7402
Lofepramine
Lofepramine (Lopramine) is a potent tricyclic antidepressant and is extensively metabolised to Desipramine. The antidepressant activity of Lofepramine stems from the facilitation of noradrenergic neurotransmission by uptake inhibition. Lofepramine may also potentiate serotoninergic neurotransmission by inhibition of the neuronal uptake of serotonin and the enzyme tryptophan pyrrolase. Lofepramine has significant anxiolytic efficacy in addition to its antidepressant properties.
-
BCC7660
LY 393558
271780-64-4
-
BCC7267
(±)-McN 5652
Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake <em>in vitro</em>
-
BCC5965
(±)-MDMA hydrochloride
92279-84-0
-
BCC6183
Mephedrone hydrochloride
1189726-22-4
-
BCC4922
Milnacipran HCl
Milnacipran hydrochloride is a serotonin-norepinephrine reuptake inhibitor (SNRI) used in the clinical treatment of fibromyalgia.
-
BCC7479
Nefazodone hydrochloride
Nefazodone hydrochloride is an antidepressant drug.
-
BCC7265
Paroxetine maleate
64006-44-6
-
BCC5059
Sertraline HCl
Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.


