Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 54

  1. Cat.No. Product Name Information/Activity
  2. BCC5252 Sibutramine hydrochloride Sibutramine hydrochloride is a novel <b>5-HT</b> (<b>serotonin</b>) and noradrenaline reuptake inhibitor (SNRI). Sibutramine hydrochloride chemical structure
  3. BCC5277 Tetrabenazine Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. Tetrabenazine chemical structure
  4. BCC2513 Venlafaxine Hydrochloride Venlafaxine hydrochloride is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. Venlafaxine Hydrochloride chemical structure
  5. BCC6125 WY 45233 succinate 448904-47-0 WY 45233 succinate chemical structure
  6. BCC7173 Zimelidine dihydrochloride 60525-15-7 Zimelidine dihydrochloride chemical structure
  7. BCC4715 Serotonin HCl Serotonin hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM. Serotonin HCl chemical structure
  8. BCC2506 Tianeptine sodium Tianeptine sodium salt is a selective facilitator of 5-HT uptake in vitro and in vivo. Tianeptine sodium chemical structure
  9. BCC6737 (±)-Vesamicol hydrochloride 120447-62-3 (±)-Vesamicol hydrochloride chemical structure
  10. BCC7553 Desipramine hydrochloride Desipramine hydrochloride is an inhibitor of norepinephrine transporter (NET), 5-HT transporter (SERT) and dopamine transporter (DAT) with Kis of 4, 61 and 78,720 nM, respectively. Desipramine hydrochloride chemical structure
  11. BCC4329 Maprotiline HCl Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant. Maprotiline HCl chemical structure

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