Alzheimer's Disease Research

Alzheimer's disease (AD), the most common type of dementia, is an irreversible and progressive neurodegenerative disorder causing cognitive and functional impairment. It is characterized by formation of protein aggregates and progressive loss of neurons in the central nervous system (CNS). The symptoms of AD include short-term memory loss, confusion, irritability, aggression and mood swings, progressing to long-term memory deficit, withdrawal from social interactions and subsequently a loss in higher central functioning.

Alzheimer's Disease Research Products Targets

Products for Alzheimer's Disease Research - Page 39

  1. Cat.No. Product Name Information/Activity
  2. BCC7234 Ro 04-5595 hydrochloride 64047-73-0 Ro 04-5595 hydrochloride chemical structure
  3. BCC4159 Ro 25-6981 Maleate Ro 25-6981 Maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. Ro 25-6981 Maleate chemical structure
  4. BCC7619 Ro 61-8048 Ro 61-8048 is a potent and selective inhibitors of kynurenine hydroxylase with IC50 of 37 nM. Ro 61-8048 chemical structure
  5. BCC7655 Ro 8-4304 hydrochloride 1312991-77-7 Ro 8-4304 hydrochloride chemical structure
  6. BCC6992 SDZ 220-040 174575-40-7 SDZ 220-040 chemical structure
  7. BCC1939 SDZ 220-581 SDZ 220-581 is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7. SDZ 220-581 chemical structure
  8. BCC6730 Synthalin sulfate 182285-12-7 Synthalin sulfate chemical structure
  9. BCC6122 TCN 201 852918-02-6 TCN 201 chemical structure
  10. BCC6123 TCN 213 556803-08-8 TCN 213 chemical structure
  11. BCC6111 TCN 237 dihydrochloride NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM; NR2B Ca2+ influx IC50 is 9.7 nM; no activities on NR2A, NR2C, NR2D, hERG-channel and α1-adrenergic receptor. TCN 237 dihydrochloride chemical structure

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