Alzheimer's Disease Research

Alzheimer's disease (AD), the most common type of dementia, is an irreversible and progressive neurodegenerative disorder causing cognitive and functional impairment. It is characterized by formation of protein aggregates and progressive loss of neurons in the central nervous system (CNS). The symptoms of AD include short-term memory loss, confusion, irritability, aggression and mood swings, progressing to long-term memory deficit, withdrawal from social interactions and subsequently a loss in higher central functioning.

Alzheimer's Disease Research Products Targets

Products for Alzheimer's Disease Research - Page 31

  1. Cat.No. Product Name Information/Activity
  2. BCC6586 Domoic acid 14277-97-5 Domoic acid chemical structure
  3. BCC6597 (S)-(-)-5-Iodowillardiine 140187-25-3 (S)-(-)-5-Iodowillardiine chemical structure
  4. BCC6572 Kainic acid Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS. Kainic acid chemical structure
  5. BCC7297 MNI caged kainic acid 1315378-75-6 MNI caged kainic acid chemical structure
  6. BCC6840 SYM 2081 SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively. SYM 2081 chemical structure
  7. BCC7462 ACET 936095-50-0 ACET chemical structure
  8. BCC7275 NS 3763 70553-45-6 NS 3763 chemical structure
  9. BCC2314 Topiramate Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels, increases in potassium conductance, and inhibition of carbonic anhydrase. Topiramate chemical structure
  10. BCC7255 UBP 296 745055-86-1 UBP 296 chemical structure
  11. BCC7172 UBP 301 569371-10-4 UBP 301 chemical structure

Items 301 to 310 of 399 total