Alzheimer's Disease Research

Alzheimer's disease (AD), the most common type of dementia, is an irreversible and progressive neurodegenerative disorder causing cognitive and functional impairment. It is characterized by formation of protein aggregates and progressive loss of neurons in the central nervous system (CNS). The symptoms of AD include short-term memory loss, confusion, irritability, aggression and mood swings, progressing to long-term memory deficit, withdrawal from social interactions and subsequently a loss in higher central functioning.

Alzheimer's Disease Research Products Targets

Products for Alzheimer's Disease Research - Page 35

  1. Cat.No. Product Name Information/Activity
  2. BCC6577 7-Chlorokynurenic acid 7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery. 7-Chlorokynurenic acid chemical structure
  3. BCC6805 (2R,3S)-Chlorpheg 140924-23-8 (2R,3S)-Chlorpheg chemical structure
  4. BCC7369 Co 101244 hydrochloride 193356-17-1 Co 101244 hydrochloride chemical structure
  5. BCC6120 Conantokin G 93438-65-4 Conantokin G chemical structure
  6. BCC5980 Conantokin-R 202925-60-8 Conantokin-R chemical structure
  7. BCC5977 Conantokin-T 127476-26-0 Conantokin-T chemical structure
  8. BCC6581 (R)-CPP 126453-07-4 (R)-CPP chemical structure
  9. BCC6561 (RS)-CPP 100828-16-8 (RS)-CPP chemical structure
  10. BCC6999 D-CPP-ene 117414-74-1 D-CPP-ene chemical structure
  11. BCC6592 5,7-Dichlorokynurenic acid 131123-76-7 5,7-Dichlorokynurenic acid chemical structure

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