Alzheimer's Disease Research

Alzheimer's disease (AD), the most common type of dementia, is an irreversible and progressive neurodegenerative disorder causing cognitive and functional impairment. It is characterized by formation of protein aggregates and progressive loss of neurons in the central nervous system (CNS). The symptoms of AD include short-term memory loss, confusion, irritability, aggression and mood swings, progressing to long-term memory deficit, withdrawal from social interactions and subsequently a loss in higher central functioning.

Alzheimer's Disease Research Products Targets

Products for Alzheimer's Disease Research - Page 28

  1. Cat.No. Product Name Information/Activity
  2. BCC7885 IEM 1925 dihydrobromide 258282-23-4 IEM 1925 dihydrobromide chemical structure
  3. BCC7476 Naspm trihydrochloride Naspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. Naspm trihydrochloride chemical structure
  4. BCC6624 NBQX NBQX is a highly selective and competitive AMPA receptor antagonist. NBQX chemical structure
  5. BCC6907 NBQX disodium salt 479347-86-9 NBQX disodium salt chemical structure
  6. BCC7478 Philanthotoxin 74 Philanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. Philanthotoxin 74 chemical structure
  7. BCC6866 SYM 2206 SYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist. SYM 2206 chemical structure
  8. BCC6378 Talampanel(LY300164) Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED). Talampanel(LY300164) chemical structure
  9. BCC7171 UBP 282 544697-47-4 UBP 282 chemical structure
  10. BCC7455 YM 90K hydrochloride 154164-30-4 YM 90K hydrochloride chemical structure
  11. BCC7339 ZK 200775 Fanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. ZK 200775 chemical structure

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