Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 33

  1. Cat.No. Product Name Information/Activity
  2. BCC7240 PSB 36 524944-72-7 PSB 36 chemical structure
  3. BCC7656 SLV 320 Derenofylline (SLV 320) is a potent, selective and orally active adenosine A1 receptor antagonist, with Ki values of 1 nM, 200 nM and 398 nM for human A1, A3 and A2A receptors respectively. Derenofylline suppresses cardiac fibrosis and attenuates albuminuria without affecting blood pressure in rats. SLV 320 chemical structure
  4. BCC7032 PD 81723 132861-87-1 PD 81723 chemical structure
  5. BCC4316 CGS 21680 HCl CGS 21680 Hydrochloride is a selective adenosine A2A receptor agonist with a Ki of 27 nM. CGS 21680 HCl chemical structure
  6. BCC7163 CV 1808 53296-10-9 CV 1808 chemical structure
  7. BCC6237 LUF 5834 333962-91-7 LUF 5834 chemical structure
  8. BCC7640 8-(3-Chlorostyryl)caffeine 147700-11-6 8-(3-Chlorostyryl)caffeine chemical structure
  9. BCC7815 ANR 94 Adenosine A<sub>2A </sub>antagonist ANR 94 chemical structure
  10. BCC3798 Istradefylline (KW-6002) Istradefylline is a very potent, selective and orally active adenosine A2A receptor antagonist with Ki of 2.2 nM in experimental models of Parkinson's disease. Istradefylline (KW-6002) chemical structure
  11. BCC7977 Lu AA 47070 913842-25-8 Lu AA 47070 chemical structure

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