Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 30

  1. Cat.No. Product Name Information/Activity
  2. BCC4146 Xanomeline oxalate Xanomeline oxalate (LY246708 oxalate) is a selective M1 muscarinic receptor agonist. Xanomeline oxalate chemical structure
  3. BCC4565 Biperiden HCl Biperiden Hydrochloride (KL 373 Hydrochloride) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker. Biperiden HCl chemical structure
  4. BCC6655 Nitrocaramiphen hydrochloride 98636-73-8 Nitrocaramiphen hydrochloride chemical structure
  5. BCC6923 Pirenzepine dihydrochloride Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist. Pirenzepine dihydrochloride chemical structure
  6. BCC6946 Telenzepine dihydrochloride 147416-96-4 Telenzepine dihydrochloride chemical structure
  7. BCC7766 VU 0255035 1135243-19-4 VU 0255035 chemical structure
  8. BCC7907 VU 0357017 hydrochloride VU0357017 hydrochloride is a highly selective M1 agonists that appear to act at an allosteric site to activate the receptor (EC50 = 477 ± 172 nM; pEC50 = 6.37 ± 0.15). VU 0357017 hydrochloride chemical structure
  9. BCC6628 Arecaidine propargyl ester tosylate 147202-94-6 Arecaidine propargyl ester tosylate chemical structure
  10. BCC6939 AF-DX 116 Otenzepad (AF-DX 116) is a selective and competitive M2 muscarinic acetylcholine receptor antagonist, with IC50 values of 640 nM and 386 nM for rabbit peripheral lung and rat heart, respectively. AF-DX 116 chemical structure
  11. BCC7024 AF-DX 384 118290-26-9 AF-DX 384 chemical structure

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