Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 31

  1. Cat.No. Product Name Information/Activity
  2. BCC7314 AQ-RA 741 Selective, high affinity M<sub>2</sub> antagonist AQ-RA 741 chemical structure
  3. BCC7061 (S)-(+)-Dimethindene maleate 136152-65-3 (S)-(+)-Dimethindene maleate chemical structure
  4. BCC6661 4-DAMP 1952-15-4 4-DAMP chemical structure
  5. BCC7263 DAU 5884 hydrochloride 131780-48-8 DAU 5884 hydrochloride chemical structure
  6. BCC7389 J 104129 fumarate 257603-40-0 J 104129 fumarate chemical structure
  7. BCC7418 Zamifenacin fumarate Zamifenacin fumarate (UK-76654 fumarate) is a potent gut-selective muscarinic M3 receptor antagonist. Zamifenacin significantly reduces colonic motility in irritable bowel syndrome. Zamifenacin fumarate chemical structure
  8. BCC7145 PD 102807 23062-91-1 PD 102807 chemical structure
  9. BCC4574 Tropicamide Tropicamide is an anticholinergic and a muscarinic receptor subtype M4-preferring antagonist . Tropicamide chemical structure
  10. BCC4053 VU0152100 VU0152100 is a potent and selective allosteric potentiator of M4 mAChR with an EC50 of 380 ± 93 nM. VU0152100 chemical structure
  11. BCC7729 VU 0238429 VU 0238429 is positive allosteric modulator of muscarinic acetylcholine receptor subtype 5 (mAChR5 or M5), with an EC50 of 1.16 μM. VU 0238429 chemical structure

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