5-HT1D Receptor
Serotonin 5-HT1D receptors, previously known as 5-HT1Dα receptors, are located primarily in the basal ganglia, hippocampus, cortex, spinal cord and vascular smooth muscle cells. 5-HT1D receptors are thought to be involved in neuropsychiatric disorders such as depression.
Products for 5-HT1D Receptor
- Cat.No. Product Name Information/Activity
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BCC7774
CP 135807
151272-90-1
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BCC7742
Donitriptan hydrochloride
5-HT<sub>1B/1D</sub> agonist
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BCC5039
Eletriptan HBr
Eletriptan HBr is a selective 5-HT1B and 5-HT1D receptor agonist with Ki of 0.92 nM and 3.14 nM, respectively.
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BCC5679
GR 46611
185259-85-2
-
BCC7437
L-703,664 succinate
144776-01-2
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BCC7408
PNU 109291
187665-60-7
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BCC7222
PNU 142633
PNU-142633 is a high affinity, selective and orally active 5-HT1D receptor agonist with Kis of 6 nM and > 18 000 nM for human 5-HT1D receptor and human 5-HT1B receptor, respectively. PNU-142633 has anti-migraine efficacy.
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BCC3852
Rizatriptan Benzoate
Rizatriptan Benzoate(Maxalt) is a 5-HT1 agonist triptan drug for the treatment of migraine headaches.
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BCC2502
Sumatriptan Succinate
Sumatriptan succinate (GR 43175) is a serotonin1 (5-HT1) receptor agonist, which is effective in the acute treatment of migraine headache.
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BCC5062
Zolmitriptan
Zolmitriptan is a novel and highly selective 5-HT(1B/1D) receptor agonist, used in the treatment of acute migraines.
