Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 25

  1. Cat.No. Product Name Information/Activity
  2. BCC6746 L-Canavanine sulfate L-Canavanine sulfate is a selective inhibitor of inducible NO synthase. L-Canavanine sulfate chemical structure
  3. BCC2865 L-NAME hydrochloride L-NAME hydrochloride inhibits NOS with an IC50 of 70 μM. L-NAME is a precursor to NOS inhibitor L-NOARG which has an IC50 value of 1.4 μM. L-NAME hydrochloride chemical structure
  4. BCC5674 7-NINA 161467-34-1 7-NINA chemical structure
  5. BCC6713 7-Nitroindazole 2942-42-9 7-Nitroindazole chemical structure
  6. BCC6788 L-NMMA acetate L-NMMA acetate is a nitric oxide synthase inhibitor of all NOS isoforms including NOS1, NOS2, and NOS3. The Ki values for nNOS (rat), eNOS (human), and iNOS (mouse) are approximately 0.18, 0.4, and 6 µM, respectively. L-NMMA acetate chemical structure
  7. BCC2864 H-Arg(NO2)-OH 2149-70-4 H-Arg(NO2)-OH chemical structure
  8. BCC6847 TRIM 25371-96-4 TRIM chemical structure
  9. BCC7928 BIMU 8 Potent 5-HT<sub>4</sub> receptor full agonist BIMU 8 chemical structure
  10. BCC4207 Cisapride 81098-60-4 Cisapride chemical structure
  11. BCC7562 CJ 033466 519148-48-2 CJ 033466 chemical structure

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