Arrhythmia Research
An arrhythmia (also known as cardiac dysrhythmia) is defined as an irregular heartbeat, and results from abnormal electrical activity in the heart. There are various different types of arrhythmia, often resulting in a heartbeat that is too fast (tachycardia) or too slow (bradycardia). Atrial and ventricular fibrillation, which are the most common cardiac arrhythmias, account for 10-20% of all deaths among adults in the Western world. The incidence of atrial fibrillation increases with age; it not only affects cardiac function, but also increases the risk of stroke and may worsen heart failure.
Arrhythmia Research Products Targets
- Voltage-gated Sodium (NaV) Channel (30)
- Voltage-gated Potassium (KV) Channel (38)
- Voltage-gated Calcium Channel (CaV) (38)
- Epithelial Sodium Channel (3)
- STIM-Orai Channel (4)
- Ryanodine Receptor (6)
- IP3 Receptor (2)
- Acid-Sensing Ion Channel (3)
- Calcium-Activated Potassium (KCa) Channel (19)
- Inward Rectifier Potassium (Kir) Channel (21)
- HCN Channel (4)
- Adrenergic β3 Receptor (12)
- Adrenergic β2 Receptor (6)
- Adrenergic β1 Receptor (7)
Products for Arrhythmia Research - Page 5
- Cat.No. Product Name Information/Activity
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BCC3918
(±)-Bay K 8644
Ca<sup>2+</sup> channel activator (L-type); aids generation of iPSCs from MEFs
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BCC7108
(S)-(-)-Bay K 8644
(S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel. (S)-(-)-Bay-K-8644 activates Ba2+ currents (IBa) (EC50=32 nM).
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BCC7050
FPL 64176
120934-96-5
-
BCC4504
Nefiracetam
Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions.
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BCC7488
ω-Agatoxin IVA
145017-83-0
-
BCC7489
ω-Agatoxin TK
158484-42-5
-
BCC4397
Amlodipine Besylate
Amlodipine besylate is a long-acting calcium channel blocker.
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BCC7107
(R)-(+)-Bay K 8644
(R)-(+)-Bay-K-8644 is a calcium channel inhibitor. (R)-(+)-Bay-K-8644 inhibits Ba2+ currents (IBa) (IC50=975 nM).
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BCC4395
Benidipine HCl
Benidipine hydrochloride is a dihydropyridine calcium channel blocker for the treatment of high blood pressure (hypertension).
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BCC7864
Bepridil hydrochloride
Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity.


