Arrhythmia Research

An arrhythmia (also known as cardiac dysrhythmia) is defined as an irregular heartbeat, and results from abnormal electrical activity in the heart. There are various different types of arrhythmia, often resulting in a heartbeat that is too fast (tachycardia) or too slow (bradycardia). Atrial and ventricular fibrillation, which are the most common cardiac arrhythmias, account for 10-20% of all deaths among adults in the Western world. The incidence of atrial fibrillation increases with age; it not only affects cardiac function, but also increases the risk of stroke and may worsen heart failure.

Arrhythmia Research Products Targets

Products for Arrhythmia Research - Page 4

  1. Cat.No. Product Name Information/Activity
  2. BCC7002 (-)-Xestospongin C 88903-69-9 (-)-Xestospongin C chemical structure
  3. BCN5807 Caffeine 58-08-2 Caffeine chemical structure
  4. BCC7808 NAADP tetrasodium salt 5502-96-5 NAADP tetrasodium salt chemical structure
  5. BCC7079 Suramin hexasodium salt Suramin sodium salt (Suramin hexasodium salt) is a reversible and competitive protein-tyrosine phosphatases (PTPases) inhibitor. Suramin sodium salt is a potent inhibitor of sirtuins: SirT1 (IC50=297 nM), SirT2 (IC50=1.15 μM), and SirT5 (IC50=22 μM). Suramin sodium salt is a competitive inhibitor of reverse transcriptase (DNA topoisomerase II: IC50=5 μM). Suramin sodium salt is an antitrypanosomal, anti-neoplastic and anti-angiogenic agent. Suramin hexasodium salt chemical structure
  6. BCC6673 Dantrolene, sodium salt 14663-23-1 Dantrolene, sodium salt chemical structure
  7. BCC7067 Ruthenium Red 11103-72-3 Ruthenium Red chemical structure
  8. BCC5742 Ryanodine Ryanodine is a cell permeant ryanodine receptor modulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+ release depending on its concentrations. Poisonous diterpenoid found in Ryania speciosa. Ryanodine chemical structure
  9. BCC6644 ML 9 hydrochloride ML-9 is a selective and potent inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK) and stromal interaction molecule 1 (STIM1) activity. ML-9 inhibits inhibits MLCK, PKA and PKC activity with Ki values of 4, 32 and 54 μM, respectively. ML-9 induces autophagy by stimulating autophagosome formation and inhibiting their degradation. ML 9 hydrochloride chemical structure
  10. BCC6953 SKF 96365 hydrochloride SKF-96365 hydrochloride is a non-selective TRP Channel blocker. SKF 96365 hydrochloride chemical structure
  11. BCC7817 YM 58483 YM-58483 is the first selective and potent inhibitor of CRAC channels and subsequent Ca2+ signals. YM 58483 chemical structure

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