Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN3198 | Corylifol A |
| Corylifol A is a naturally occurring potent inhibitor of hCE2 and UDP-glucuronosyltransferase 1A1 (UGT1A1); it could be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. Corylifol A has antiinflammatory activity, it shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uΜ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells. | |
| BCN3200 | Corylifol C |
| 1. Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/ml, respectively). | |
| BCN3207 | Ganoderic acid TR |
| 1. Ganoderic acid TR, a new lanostanoid with 5α-reductase inhibitory activity from the fruiting body of Ganoderma lucidum. | |
| BCN3208 | Ganoderenic acid A |
| 1. Ganoderenic acid A show inhibitory activity on human aldose reductase in vitro. 2. Ganoderenic acid A has a potent hepatoprotective effect against CCl4-induced liver injury. 3. Ganoderenic acid A has cytotoxic activity, their inhibitory activities against human HeLa cervical cancer cell lines. | |
| BCN3218 | 6,7-Dehydroferruginol |
| 1. 6,7-Dehydroferruginol has potent activity against F. palustris . 2. 6,7-Dehydroferruginol and sugiol are weakly active against Heterosigma akashiwo. | |
