Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2930 | Glycyrrhisoflavone |
| Glycyrrhisoflavone is a tyrosinase inhibitor, it also shows inhibitory effects on monoamine oxidase. Glycybenzofuran shows significant protein tyrosine phosphatase-1B (PTP1B) inhibitory activity in vitro with the IC50 value of 25.5 microM. Glycyrrhisoflavone has anti-inflammatory effects, it has significant inhibitory effects against NO production on LPS-induced RAW 264.7 cell model. | |
| BCN2932 | Mauritianin |
| 1. Mauritianin and (+)-syringaresinol as new topoisomerase I inhibitors. 2. Mauritianin has statistically significant cytoprotective activity similar to that of silymarin, tested at 60 ug/mL. | |
| BCN2939 | Cassiaside |
| 1. Cassiaside and emodi show mixed-type inhibition against β-site amyloid precursor protein (APP) cleaving enzyme 1 (BACE1). 2. Cassiaside demonstrates significant antimutagenic activity. 3. Cassiaside shows 1,1-diphenyl-2-picrylhydrazyl(DPPH) radical scavenging effect. 4. Cassiaside has significant hepato-protective effects against galactosamine damage, which is higher than that of silybin from Silybum marianum. | |
| BCN2949 | Irinotecan hydrochloride |
| Irinotecan hydrochloride is a water soluble topoisomerase I inhibitor mainly used to treat colon cancer and rectal cancer. | |
| BCN2954 | Desoxyrhaponticin |
| Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes. Desoxyrhaponticin could be considered as a promising fatty acid synthase(FAS) inhibitor, it could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. | |
