Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCC3917 | 8'-Epicleomiscosin A |
| 8'-Epicleomiscosin A shows strong inhibition (IC50=1.33 microM) against the enzyme tyrosinase, as compared to the standard tyrosinase inhibitors kojic acid (IC50=16.67 microM) and L-mimosine (IC50=3.68 microM), indicating its potential used for the treatment of hyperpigmentation associated with the high production of melanocytes. | |
| BCC8134 | Bornyl isobutyrate |
| meso-Hannokinol and (+)-hannokinol can significantly inhibit lipopolysaccharide-induced nitric oxide production in BV2 microglial cells at concentrations ranging from 1 uM to 100 uM. | |
| BCC8411 | Dibutyl Phthalate |
| 1,2-Benzenedicarboxylic acid is one kind of allelochemical shows stronger allelopathic effect on itself than on wheat and pigeonpea. 1,2-Benzenedicarboxylic acid has antimicrobial activity, it shows anti-extended-spectrum beta-lactamases (ESBL) activity. | |
| BCN1012 | Madecassoside |
| Madecassoside is a mechanism-based inhibitor of CYP2C19 and CYP3A4, which has antioxidant, anti-inflammatory, anti-apoptosis, wound-healing, and neuroprotective activities, It may have cardioprotective effects in LPS-mediated through inhibition of ERK, p38, and NF-κB activity, it inhibited the pro-inflammatory mediators, including COX-2 expression, PGE2 production, TNF-αand IL-6 levels and the up-regulation anti-inflammatory molecule IL-10. | |
| BCN1018 | Piperine |
| Piperine, an inhibitor of human P-glycoprotein and/or CYP3A4, which has antinociceptive, antiarthritic, antidepressant, hepatoprotective, immunomodulatory , antitumor, anti-oxidative, anti-apoptotic, chemo-protective, and anti-inflammatoryactivities. Administration of piperine appears to reverse preexisting high-fat diet (HFD)-induced hepatic steatosis and insulin resistance, probably by activation of adiponectin-AMPK signalling. | |
