Pain and Inflammation Research

Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.

Pain and Inflammation Research Products Areas

Products for Pain and Inflammation Research - Page 53

Cat.No. Product Name Information/Activity
BCC7535 NS 1738 NS 1738 (NSC 213859) is a novel positive allosteric modulator of the α7 nAChR, with respect to positive modulation of α7 nAChR (EC50=3.4 μM in oocyte experiments).
BCC4581 PNU-120596 PNU-120596 (NSC 216666 ) is a potent and selective positive allosteric α7 nAChR modulator with an EC50 of 0.2 μM.
BCC7896 TQS 353483-92-8
BCC7564 FR 236924 DCP-LA (FR236924), a linoleic acid derivative, selectively and directly activates PKCε.
BCC5756 Noladin ether 222723-55-9
BCC6827 Oleamide Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.
BCC4412 AM251 AM251 is a selective cannabinoid 1 (CB1) receptor antagonist with an IC50 of 8 nM, also acts as a potent GPR55 agonist with an EC50 of 39 nM.
BCC6944 AM 281 Potent, selective CB<sub>1</sub> antagonist/inverse agonist
BCC1082 CP-945598 HCl Otenabant Hydrochloride is a potent and selective cannabinoid receptor CB1 antagonist with Ki of 0.7 nM, exhibits 10,000-fold greater selectivity against human CB2 receptor.
BCC6065 Hemopressin (human, mouse) 1314035-51-2