Pain and Inflammation Research
Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.
Pain and Inflammation Research Products Areas
Products for Pain and Inflammation Research - Page 46
- Cat.No. Product Name Information/Activity
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BCC8091
U 73343
U-73343, an inhibitor of PLC (putative phospholipase C)-dependent processes, is an analog of U-73122 and can be used as a negative control.
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BCC7715
VU 0155069
VU0155069 (CAY10593), compound 69, is a selective phospholipase D1 (PLD1) inhibitor with an IC50 value of 46 nM in vitro. VU0155069 (CAY10593) strongly inhibits the invasive migration of several cancer cell lines in transwell assays.
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BCC7875
VU 0364739 hydrochloride
1244640-48-9
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BCC7396
YM 26734
144337-18-8
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BCC7209
m-3M3FBS
200933-14-8
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BCC7210
o-3M3FBS
313981-55-4
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BCC3715
A66
A66 is a highly specific and selective p110α inhibitor with an IC50 of 32 nM.
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BCC4988
AS-252424
AS-252424 is a potent and selective PI3Kγ inhibitor with an IC50 of 30±10 nM.
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BCC2495
AS-605240
AS-605240 is a specific and orally active inhibitor of the PI3Kγ, with an IC50 of 8 nM, and a Ki of 7.8 nM.
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BCC2523
AZD6482
AZD 6482 (KIN-193) is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.
