Pain and Inflammation Research
Although separate conditions, pain and inflammation are nearly always associated with each other. Pain is defined by the International Association for the Study of Pain (IASP) as 'an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage'. Inflammation is the tissue's immunologic response to injury, characterized by mobilization of white blood cells and antibodies, swelling, and fluid accumulation.
Pain and Inflammation Research Products Areas
Products for Pain and Inflammation Research - Page 57
- Cat.No. Product Name Information/Activity
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BCC5957
DPNI-caged-GABA
Nitroindoline-caged GABA
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BCC6575
Isoguvacine hydrochloride
Isoguvacine hydrochloride is a GABA receptor agonist.
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BCC7617
L-838,417
286456-42-6
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BCC6170
MK 0343
MK0343 (MRK-409) is an orally bioavailable GABAA receptor subtype-selective partial agonist. MK0343 is a non-sedating anxiolytic.
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BCC6070
MRK 016
783331-24-8
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BCC6593
Muscimol
Potent GABA<sub>A</sub> agonist
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BCC6564
TACA
38090-53-8
-
BCC7819
TCS 1205
355022-97-8
-
BCC6803
THIP hydrochloride
Gaboxadol hydrochloride (Lu 02-030 hydrochloride; THIP hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors (IC50=25 μM). Gaboxadol hydrochloride displays a partial agonist efficacy on subunit α1β2γ2 with an ED50 value of 143 µM, a full agonist efficacy at α5 subunit (ED50=28-129 µM) and a superagonist efficacy at α4β3δ (ED50=6 µM). Gaboxadol hydrochloride is a non-opioid analgesic and has hypnotic activities.
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BCC6169
TP 003
628690-75-5


