Huntington's Disease Research

Huntington's disease is a neurodegenerative disease characterized by cognitive decline and motor dysfunction. It is a genetic disorder which results in the production of mutant huntingtin protein (mHtt). This protein aggregates in the cell cytoplasm and nucleus, affecting cellular function.

Huntington's Disease Research Products Targets

Products for Huntington's Disease Research - Page 20

Cat.No. Product Name Information/Activity
BCC6978 2-APB 2-Aminoethyl diphenylborinate (2-APB) is a cell-permeable inhibitor of IP3R. 2-Aminoethyl diphenylborinate also inhibits the store-operated Ca2+ (SOC) channel and activates some TRP channels (V1, V2 and V3).
BCC7002 (-)-Xestospongin C 88903-69-9
BCC6940 ATPA ATPA is a selective glutamate receptor GluR5 activator with EC50s of 0.66, 9.5, 1.4, 23, 32, 18, and 14 μM for GluR5wt, GluR5(S741M), GluR5(S721T), GluR5(S721T, S741M), GluR5(S741A), GluR5(S741L), and GluR5(S741V), respectively.
BCC6586 Domoic acid 14277-97-5
BCC6597 (S)-(-)-5-Iodowillardiine 140187-25-3
BCC6572 Kainic acid Kainic acid is a potent agonist at excitatory amino acid receptor subtypes in the CNS.
BCC7297 MNI caged kainic acid 1315378-75-6
BCC7462 ACET 936095-50-0
BCC6569 CNQX CNQX (FG9065) is a potent AMPA/kainate receptor antagonist.
BCC6908 CNQX disodium salt 479347-85-8