Huntington's Disease Research

Huntington's disease is a neurodegenerative disease characterized by cognitive decline and motor dysfunction. It is a genetic disorder which results in the production of mutant huntingtin protein (mHtt). This protein aggregates in the cell cytoplasm and nucleus, affecting cellular function.

Huntington's Disease Research Products Targets

Products for Huntington's Disease Research - Page 14

Cat.No. Product Name Information/Activity
BCC3773 Duloxetine HCl Duloxetine hydrochloride ((S)-Duloxetine hydrochloride) is a serotonin-norepinephrine reuptake inhibitor (SNRI) with a Ki of 4.6 nM, used for treatment of major depressive disorder and generalized anxiety disorder (GAD).
BCC6676 GBR 12783 dihydrochloride GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor that inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively. GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats.
BCC5129 Vanoxerine dihydrochloride Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) is a competitive, potent, and highly selective dopamine reuptake inhibitor (Ki=1 nM). Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) binds to the target site on the dopamine transporter (DAT).
BCC5380 GBR 12935 dihydrochloride GBR 12935 dihydrochloride is a potent, and selective dopamine reuptake inhibitor.
BCC6640 GBR 13069 dihydrochloride 67469-45-8
BCC7123 Indatraline hydrochloride 96850-13-4
BCC7923 JHW 007 hydrochloride 202645-74-7
BCC7267 (±)-McN 5652 Potent, orally active 5-HT uptake inhibitor. Also inhibits noradrenalin and dopamine uptake <em>in vitro</em>
BCC5965 (±)-MDMA hydrochloride 92279-84-0
BCC6183 Mephedrone hydrochloride 1189726-22-4