Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 58

  1. Cat.No. Product Name Information/Activity
  2. BCC1487 Clozapine N-oxide (CNO) Activator of muscarinic DREAADs,Clozapine N-oxide is a pharmacologically inert metabolite of Clozapine, which is a potent <b>5-HT1C</b> receptor antagonist. Clozapine N-oxide (CNO) chemical structure
  3. BCC6202 DV 7028 hydrochloride 133364-62-2 DV 7028 hydrochloride chemical structure
  4. BCC6678 4F 4PP oxalate 144734-36-1 4F 4PP oxalate chemical structure
  5. BCC7440 Fananserin Fananserin (RP 62203) is an orally bioavailable, potent and selective 5-hydroxytryptamine2 (5-HT2) receptor antagonist, with a Ki of 0.37 nM for the rat 5-HT2A receptor. Fananserin also is a selective dopamine D4 receptor antagonist, with a Ki of 2.93 nM for the human dopamine D4 receptor. Fananserin chemical structure
  6. BCC7877 MDL 100907 Volinanserin is a potent and selective antagonist of 5-HT2 receptor, with a Ki of 0.36 nM, and shows 300-fold selectivity for 5-HT2 receptor over 5-HT1c, alpha-1 and DA D2 receptors. Volinanserin has antipsychotic activity. MDL 100907 chemical structure
  7. BCC6822 MDL 11,939 107703-78-6 MDL 11,939 chemical structure
  8. BCC7385 Melperone hydrochloride 1622-79-3 Melperone hydrochloride chemical structure
  9. BCC7139 Mesulergine hydrochloride 72786-12-0 Mesulergine hydrochloride chemical structure
  10. BCC7479 Nefazodone hydrochloride Nefazodone hydrochloride is an antidepressant drug. Nefazodone hydrochloride chemical structure

Items 571 to 580 of 607 total