Hypertension Research

Hypertension is defined as a chronic elevation in blood pressure with a systolic pressure over 140 mmHg and a diastolic pressure over 90 mmHg.The majority of hypertension is primary - that is, an increase in blood pressure with no underlying cause - yet pathologies that affect the kidney or endocrine system may also trigger hypertension. This is known as secondary hypertension. The exact mechanism of primary hypertension is yet to be elucidated, though dysfunctions in mechanisms that regulate vascular tone, both directly and indirectly, have been identified as having a major influence on hypertension.

Hypertension Research Products Targets

Products for Hypertension Research - Page 53

  1. Cat.No. Product Name Information/Activity
  2. BCC5034 Aripiprazole Aripiprazole (OPC-14597) is a human 5-HT1A receptor partial agonist with a Ki of 4.2 nM. Aripiprazole chemical structure
  3. BCC7657 ATC 0175 hydrochloride MCH<sub>1</sub> antagonist; also 5-HT<sub>2B</sub> antagonist and 5-HT<sub>1A</sub> partial agonist ATC 0175 hydrochloride chemical structure
  4. BCC6695 BP 554 maleate Selective 5-HT<sub>1A</sub> agonist BP 554 maleate chemical structure
  5. BCC6929 (R)-(+)-8-Hydroxy-DPAT hydrobromide 78095-19-9 (R)-(+)-8-Hydroxy-DPAT hydrobromide chemical structure
  6. BCC6800 8-Hydroxy-PIPAT oxalate 1451210-48-2 8-Hydroxy-PIPAT oxalate chemical structure
  7. BCC7201 Ipsapirone 95847-70-4 Ipsapirone chemical structure
  8. BCC6636 MDL 73005EF hydrochloride 102908-60-1 MDL 73005EF hydrochloride chemical structure
  9. BCC7165 Nemonapride 75272-39-8 Nemonapride chemical structure
  10. BCC7174 S 14506 hydrochloride 286369-38-8 S 14506 hydrochloride chemical structure
  11. BCC2502 Sumatriptan Succinate Sumatriptan succinate (GR 43175) is a serotonin1 (5-HT1) receptor agonist, which is effective in the acute treatment of migraine headache. Sumatriptan Succinate chemical structure

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