Ligupurpuroside CCAS# 1194056-33-1 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 1194056-33-1 | SDF | Download SDF |
| PubChem ID | 125181921 | Appearance | Powder |
| Formula | C35H46O17 | M.Wt | 738.73 |
| Type of Compound | Phenylpropanoids | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | [(2R,3R,4S,5R,6R)-4-[(2S,3R,4S,5R,6S)-3,4-dihydroxy-6-methyl-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-3,5-dihydroxy-6-[2-(4-hydroxyphenyl)ethoxy]oxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate | ||
| SMILES | CC1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(C(OC(C3O)OCCC4=CC=C(C=C4)O)COC(=O)C=CC5=CC=C(C=C5)O)O)C)O)O)O | ||
| Standard InChIKey | ZPGBMGMUFKRLER-CMPWVXOTSA-N | ||
| Standard InChI | InChI=1S/C35H46O17/c1-16-24(39)26(41)28(43)34(48-16)51-31-17(2)49-35(29(44)27(31)42)52-32-25(40)22(15-47-23(38)12-7-18-3-8-20(36)9-4-18)50-33(30(32)45)46-14-13-19-5-10-21(37)11-6-19/h3-12,16-17,22,24-37,39-45H,13-15H2,1-2H3/b12-7+/t16-,17-,22+,24-,25+,26+,27-,28+,29+,30+,31-,32-,33+,34-,35-/m0/s1 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
||
| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
||
| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | 1. Ligupurpuroside C can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 umol/L. 2. Ligupurpuroside C has antioxidant activity. |
| Targets | AMPK |
Ligupurpuroside C Dilution Calculator
Ligupurpuroside C Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 1.3537 mL | 6.7684 mL | 13.5367 mL | 27.0735 mL | 33.8419 mL |
| 5 mM | 0.2707 mL | 1.3537 mL | 2.7073 mL | 5.4147 mL | 6.7684 mL |
| 10 mM | 0.1354 mL | 0.6768 mL | 1.3537 mL | 2.7073 mL | 3.3842 mL |
| 50 mM | 0.0271 mL | 0.1354 mL | 0.2707 mL | 0.5415 mL | 0.6768 mL |
| 100 mM | 0.0135 mL | 0.0677 mL | 0.1354 mL | 0.2707 mL | 0.3384 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
Calcutta University
University of Minnesota
University of Maryland School of Medicine
University of Illinois at Chicago
The Ohio State University
University of Zurich
Harvard University
Colorado State University
Auburn University
Yale University
Worcester Polytechnic Institute
Washington State University
Stanford University
University of Leipzig
Universidade da Beira Interior
The Institute of Cancer Research
Heidelberg University
University of Amsterdam
University of Auckland
TsingHua University
The University of Michigan
Miami University
DRURY University
Jilin University
Fudan University
Wuhan University
Sun Yat-sen University
Universite de Paris
Deemed University
Auckland University
The University of Tokyo
Korea University
- Isorosmanol
Catalog No.:BCN8582
CAS No.:93780-80-4
- Isoginsenoside Rh3
Catalog No.:BCN8581
CAS No.:166040-90-0
- Uvarigrin
Catalog No.:BCN8580
CAS No.:200563-11-7
- 4-Benzamido-2,5-diethoxybenzenediazonium
Catalog No.:BCN8579
CAS No.:5486-84-0
- Hexamethylquercetagetin
Catalog No.:BCN8578
CAS No.:1251-84-9
- Epitheaflagallin 3-O-gallate
Catalog No.:BCN8577
CAS No.:102067-92-5
- 5,6-Dehydroginsenoside Rd
Catalog No.:BCN8576
CAS No.:1268459-68-2
- Jionoside D
Catalog No.:BCN8575
CAS No.:120406-34-0
- Tectol
Catalog No.:BCN8574
CAS No.:24449-39-6
- Perisesaccharide B
Catalog No.:BCN8573
CAS No.:1095261-93-0
- 4'-O-Methylochnaflavone
Catalog No.:BCN8572
CAS No.:49619-87-6
- 2-Amino-3-carboxy-1,4-naphthoquinone
Catalog No.:BCN8571
CAS No.:173043-38-4
- Lucidin 3-O-primeveroside
Catalog No.:BCN8584
CAS No.:29706-59-0
- Platycodin D3
Catalog No.:BCN8585
CAS No.:67884-03-1
- Sarracenin
Catalog No.:BCN8586
CAS No.:59653-37-1
- Glyasperin C
Catalog No.:BCN8587
CAS No.:142474-53-1
- Rubiayannone A
Catalog No.:BCN8588
CAS No.:517978-25-1
- Hydroquinidine
Catalog No.:BCN8589
CAS No.:1435-55-8
- Aaptamine
Catalog No.:BCN8590
CAS No.:85547-22-4
- Firmanoic acid
Catalog No.:BCN8591
CAS No.:107584-83-8
- Licoflavone B
Catalog No.:BCN8592
CAS No.:91433-17-9
- Cinobufaginol
Catalog No.:BCN8593
CAS No.:6691-83-4
- Jasminoside B
Catalog No.:BCN8594
CAS No.:214125-04-9
- Ophiopogonoside A
Catalog No.:BCN8595
CAS No.:791849-22-4
Hypolipidemic activity and mechanisms of the total phenylpropanoid glycosides from Ligustrum robustum (Roxb.) Blume by AMPK-SREBP-1c pathway in hamsters fed a high-fat diet.[Pubmed:29468762]
Phytother Res. 2018 Apr;32(4):715-722.
The aim of this study was to evaluate the hypolipidemic effect and mechanisms of total phenylpropanoid glycosides extracted from Ligustrum robustum (Roxb.) Blume (LRTPG) in hamsters fed a high-fat diet and to discover bioactive components in HepG2 cell model induced by oleic acid. LRTPG of high (1.2 g/kg), medium (0.6 g/kg), and low (0.3 g/kg) doses was administrated daily for 21 consecutive days in hamsters. We found that in hamsters fed a high-fat diet, LRTPG effectively reduced the concentrations of plasma triglycerides (TG), free fatty acid, total cholesterol, low-density lipoprotein cholesterol, and hepatic TG and total cholesterol. And the compounds acteoside, ligupurpuroside A, Ligupurpuroside C, and ligupurpuroside D significantly inhibited lipid accumulation in HepG2 cell at the concentration of 50 mumol/L. Mechanism research demonstrated that LRTPG increased the levels of phospho-AMP-activated protein kinase and phospho-sterol regulatory element binding protein-1c in liver, further to suppress the downstream lipogenic genes as stearoyl-CoA desaturase 1, glycerol-3-phosphate acyltransferase, 1-acylglycerol-3-phosphate O-acyltransferase 2, and diacylglycerol acyltransferase 2. In addition, LRTPG increased the hydrolysis of circulating TG by up-regulating lipoprotein lipase activities. These results indicate that LRTPG prevents hyperlipidemia via activation of hepatic AMP-activated protein kinase-sterol regulatory element binding protein-1c pathway.
Antioxidative glycosides from the leaves of Ligustrum robustum.[Pubmed:12828473]
J Nat Prod. 2003 Jun;66(6):851-4.
Phytochemical investigation of the ethanol extract of the leaves of Ligustrum robustum, monitored by a bioassay involving the hemolysis of red blood cells induced by 2,2'-azo-bis(2-amidinopropane) dihydrochloride, led to the isolation of three new glycosides, ligurobustosides M (1), N (2), and O (3), along with 10 known ones, osmanthuside B (4), osmanthuside B6 (5), acteoside (6), ligupurpuroside A (7), ligupurpuroside B (8), ligurobustoside C (9), ligurobustoside E (10), ligurobustoside I (11), cosmosiin (12), and rhoifolin (13). The structures of the new compounds were elucidated by spectroscopic methods. Seven of the glycosides showed stronger antioxidant effects than the standard, trolox.
