AverantinCAS# 5803-62-3 |
Quality Control & MSDS
Number of papers citing our products
Chemical structure
3D structure
| Cas No. | 5803-62-3 | SDF | Download SDF |
| PubChem ID | 22049 | Appearance | Powder |
| Formula | C20H20O7 | M.Wt | 372.37 |
| Type of Compound | Anthraquinones | Storage | Desiccate at -20°C |
| Solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | ||
| Chemical Name | 1,3,6,8-tetrahydroxy-2-(1-hydroxyhexyl)anthracene-9,10-dione | ||
| SMILES | CCCCCC(C1=C(C=C2C(=C1O)C(=O)C3=C(C=C(C=C3C2=O)O)O)O)O | ||
| Standard InChIKey | WGPOPPKSQRZUTP-UHFFFAOYSA-N | ||
| Standard InChI | InChI=1S/C20H20O7/c1-2-3-4-5-12(22)17-14(24)8-11-16(20(17)27)19(26)15-10(18(11)25)6-9(21)7-13(15)23/h6-8,12,21-24,27H,2-5H2,1H3 | ||
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months. We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months. Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it. |
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| About Packaging | 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial. 2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial. 3. Try to avoid loss or contamination during the experiment. |
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| Shipping Condition | Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request. | ||
| Description | Averantin exhibits antifungal activity against Fusariumsolani, pathogenic fungus of P. notoginseng, with minimum inhibitory concentrations (MICs) of 16-32 ug/mL, and shows antibacterial activity against Bacillussubtilis with MICs of 16-32 ug/mL. |
| Targets | Antifection |
| In vitro | The antifungal metabolites obtained from the rhizospheric Aspergillus sp. YIM PH30001 against pathogenic fungi of Panax notoginseng.[Pubmed: 25022791 ]Nat Prod Res. 2014;28(24):2334-7.
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Averantin Dilution Calculator
Averantin Molarity Calculator
| 1 mg | 5 mg | 10 mg | 20 mg | 25 mg | |
| 1 mM | 2.6855 mL | 13.4275 mL | 26.855 mL | 53.71 mL | 67.1375 mL |
| 5 mM | 0.5371 mL | 2.6855 mL | 5.371 mL | 10.742 mL | 13.4275 mL |
| 10 mM | 0.2686 mL | 1.3428 mL | 2.6855 mL | 5.371 mL | 6.7138 mL |
| 50 mM | 0.0537 mL | 0.2686 mL | 0.5371 mL | 1.0742 mL | 1.3428 mL |
| 100 mM | 0.0269 mL | 0.1343 mL | 0.2686 mL | 0.5371 mL | 0.6714 mL |
| * Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations. | |||||
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The antifungal metabolites obtained from the rhizospheric Aspergillus sp. YIM PH30001 against pathogenic fungi of Panax notoginseng.[Pubmed:25022791]
Nat Prod Res. 2014;28(24):2334-7.
Eight anthraquinones (1-8), three xanthones (11-13) and two phenols (9-10) were isolated from Aspergillus sp. associated with Panax notoginseng, and their structures were determined as ziganein-1-methyl ether (1), 8-O-methylchrysophanol (2), averythrin (3), averufin (4), 8-O-methyl averufin (5), versicolorin B (6), Averantin (7), methyl-Averantin (8), arugosin C (9), diorcinol (10), sterigmatocystin (11), demethylsterigmatocystin (12) and dihydrosterigmatocystin (13) by spectroscopic analyses. Compounds 1, 2 and 5 were the novel isolates from genus Aspergillus. Compounds 3, 6 and 7 exhibited antifungal activity against Fusariumsolani, pathogenic fungus of P. notoginseng, with minimum inhibitory concentrations (MICs) of 16-32 mug/mL, and compounds 1, 3, 4, 7 and 9 showed antibacterial activity against Bacillussubtilis with MICs of 64-128 mug/mL, 16-32 mug/mL, 8-16 mug/mL, 16-32 mug/mL and 64-128 mug/mL, respectively. The metabolites showed the potential value in the research of antifungal agents, especially in searching for a biocontrol of diseases of P. notoginseng. The preliminary structure-activity relationships have been discussed for some of the compounds.
