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Fmoc-Arg(NO2)-OH

CAS# 58111-94-7

Fmoc-Arg(NO2)-OH

Catalog No. BCC2596----Order now to get a substantial discount!

Product Name & Size Price Stock
Fmoc-Arg(NO2)-OH:25g $199.00 In stock
Fmoc-Arg(NO2)-OH:50g $338.00 In stock
Fmoc-Arg(NO2)-OH:125g $796.00 In stock
Fmoc-Arg(NO2)-OH:250g $1393.00 In stock
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Quality Control of Fmoc-Arg(NO2)-OH

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Chemical structure

Fmoc-Arg(NO2)-OH

3D structure

Chemical Properties of Fmoc-Arg(NO2)-OH

Cas No. 58111-94-7 SDF Download SDF
PubChem ID 12096824 Appearance Powder
Formula C21H23N5O6 M.Wt 441.44
Type of Compound N/A Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
SMILES C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NC(CCCN=C(N)N[N+](=O)[O-])C(=O)O
Standard InChIKey RXMHIKWOZKQXCJ-SFHVURJKSA-N
Standard InChI InChI=1S/C21H23N5O6/c22-20(25-26(30)31)23-11-5-10-18(19(27)28)24-21(29)32-12-17-15-8-3-1-6-13(15)14-7-2-4-9-16(14)17/h1-4,6-9,17-18H,5,10-12H2,(H,24,29)(H,27,28)(H3,22,23,25)/t18-/m0/s1
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Fmoc-Arg(NO2)-OH Dilution Calculator

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Fmoc-Arg(NO2)-OH Molarity Calculator

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Preparing Stock Solutions of Fmoc-Arg(NO2)-OH

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2653 mL 11.3266 mL 22.6531 mL 45.3063 mL 56.6328 mL
5 mM 0.4531 mL 2.2653 mL 4.5306 mL 9.0613 mL 11.3266 mL
10 mM 0.2265 mL 1.1327 mL 2.2653 mL 4.5306 mL 5.6633 mL
50 mM 0.0453 mL 0.2265 mL 0.4531 mL 0.9061 mL 1.1327 mL
100 mM 0.0227 mL 0.1133 mL 0.2265 mL 0.4531 mL 0.5663 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Fmoc-Arg(NO2)-OH

Studies on lactam formation during coupling procedures of N alpha-N omega-protected arginine derivatives.[Pubmed:8738983]

Pept Res. 1996 Mar-Apr;9(2):88-91.

We evaluated the quantity of delta-lactam generated during the synthesis of arginine-containing dipeptides using Z-Arg(Tos)-OH, Boc-Arg(Tos)-OH, Fmoc-Arg(Boc)2-OH and Fmoc-Arg(Pmc)-OH and assayed several carboxyl-activating procedures for coupling the protected arginines to different amino components. We observed significant amounts of delta-lactam during the synthesis of Z-Arg(Tos)-methyl ester and Z-Arg(Tos)-amide, as well as of Boc-Arg(Tos)-chloromethyl ketone. The mixed anhydride coupling procedure and the di-Boc-protecting guanidino group induced more delta-lactam formation than any other coupling or NG-protection method. The amide, benzyl, 4-(NO2)-benzyl and methyl alpha-carboxyl-protected amino acids generated more delta-lactam than did those protected by tertbutyl or N2H2-Boc. So far it has not been possible to propose a general mechanism for delta-lactam formation or a process that completely abolishes it. Therefore, this side reaction should be considered almost inevitable. Its minimization requires examination of arginine-containing peptides in each specific synthesis.

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