Products with Toxicity bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2503 | Kaempferol-3-beta-O-glucuronide |
| 1. Kaempferol-3-beta-O-glucuronide has antioxidant activity. 2. Flavonoid glucuronides can be deconjugated by microsomal β-glucuronidase from various human cells. | |
| BCN2651 | Berberrubine |
| Berberrubine possesses diverse pharmacological activities, including glucose-lowering, lipid-lowering, anti-inflammatory, and anti-tumor effects. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the media and mRNA expression of the cells stimulated with IL-1beta or TNF-alpha. | |
| BCN2701 | alpha-Solanine |
| 1. Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut. 2. Alpha-Solanine has proliferation-inhibiting and apoptosis-promoting effect on multiple cancer cells, such as clone, liver, melanoma cancer cells. | |
| BCN2751 | 7Beta-Hydroxycholesterol |
| 7beta-Hydroxycholesterol, a major cytotoxin in oxidized LDL, induces Ca(2+) oscillations, MAP kinase activation and apoptosis in human aortic smooth muscle cells. 7beta-Hydroxycholesterol and 7-ketocholesterol have dual cytotoxic effects on the cells of the vascular wall by their ability to induce apoptosis in endothelial and smooth muscle cells and necrosis in fibroblasts. 7beta-Hydroxycholesterol can inhibit the proliferation of NCI-H460 cells through apoptosis via caspase activation. It can reinforce the susceptibility of K562 adriamycin-resistant cells to this drug, it also can enhance radiosensitivity in RDM4 cells. | |
| BCN2797 | 3-Deoxyaconitine |
| 3-Deoxyaconitine has toxicity. | |
