Products with Toxicity bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2063 | Isoline |
| 1. Isoline decreases the cellular GSH and the ratio of GSH and oxidizes glutathione in a time- and concentration-dependent manner in L-02 cells. 2. Isoline can induce different oxidative injury in various important mouse organs, and of which liver is the most sensitive organ. 3. An in silico drug target searching program INVDOCK identified 2 potential protein targets of Isoline. 4. l-Buthionine-(S, R)-sulfoximine (BSO) and mercaptosuccinic acid (MA), inhibitors of GCL and GPx, both augmented Isoline-induced cytotoxicity in cultured mice hepatocytes. | |
| BCN2087 | Jacobine |
| 1. Jacobine induces significant dose-dependent DNA-DNA interstrand cross-linking over the entire range of doses. 2. Jacobine, was catalyzed by guinea pig hepatic glutathione-S-transferase enzymes in in vitro experiments. | |
| BCN2088 | Jacoline |
| 1. Jacoline, jaconine, jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer. 2. Jacoline, jacobine and jaconine show toxic side-effects. | |
| BCN2089 | Jaconine |
| 1. Jaconine, jacoline,jacobine, and jacozine, the hepatotoxic alkaloids, are potentially carcinogenic, mutagenic, and teratogenic and may pose health hazards to the human consumer. 2. Jaconine, jacobine and jacoline show toxic side-effects. | |
| BCN2107 | Otosenine |
| 1. D-Otocenine elicites low toxicity, it shows spasmolytic properties . | |
