Products with Toxicity bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN5384 | Atractylic acid dipotassium salt |
| 1. Atractyloside potassium salt inhibits oxidative phosphorylation by blocking the transfer of adenosine nucleotides through the mitochondrial membrane. | |
| BCN5547 | Artemetin |
| Artemetin has anti-inflammatory, antioxidant and antiapoptotic activities, it protects endothelial function through the activation of ERK1/2 and Akt. Intravenous injection of Artemetin (0.75 mg/kg) significantly reduces the hypertensive response to angiotensin I while increases the average length of bradykinin-induced hypotension. | |
| BCN5559 | Isosakuranetin |
| Isosakuranetin is a plant exudate with known cytotoxic and fungicide properties, it may act on wheat root segments as an inhibitor of K+ permeation. Isosakuranetin is a TRPM3 blocker, significantly reduces the sensitivity of mice to noxious heat and PregS-induced chemical pain; it induced- inhibition of ERK1/2 and PI3K/AKT signaling pathways activate MITF and subsequent expression of Tyr, TRP1, and TRP2. | |
| BCN5733 | beta-Yohimbine |
| 1. Beta-Yohimbine has anti-plasmodial and anti-malarial activity. 2. Beta-Yohimbine has approximately twice as toxic as yohimbine and corynanthine about one fifth as toxic. 3. Beta-yohimbine has alpha-1 and alpha-2 adrenoceptor blocking activities, it has cardiovascular effects. | |
| BCN5763 | Tanshinone IIA |
| Tanshinone IIA is an estrogen receptor partial agonist with antiandrogenic properties, it has neuroprotective effects against cerebral ischemia/reperfusion injury and traumatic injury of the spinal cord in rats. Tanshinone IIA has anti-leukemia, anti-inflammatory and anti-oxidative properties, inhibits the release of inflammatory cytokines, such as, IL-1 β, IL-6 α, TNF-α. | |
