Products with Inhibitors bioactivity
| Cat.No. | Product Name |
|---|---|
| BCN2670 | Corytuberine |
| 1. Corytuberine was inhibited only by naloxone and that of bulbocapnine preferentially by yohimbine. | |
| BCN2677 | Dihydrokavain |
| Dihydrokavain may play an important role in regulation of GABAergic neurotransmission, it non-competitively inhibits the specific binding of [3H]-batrachotoxinin-A 20-alpha-benzoate to receptor site 2 of voltage-gated Na+ channels. Dihydrokavain may treat sleep disturbances, as well as stress and anxiety. | |
| BCN2678 | Embelin |
| Embelin is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.Embelin has antitumor, antioxidant and anti-inflammatory activities. Embelin can enhance TRAIL-induced cell apoptosis through DR4 and DR5 upregulation and decrease IL-6-induced STAT3 phosphorylation, that combination of low-toxicity Embelin and TRAIL may become as a potential antileukemia strategy. | |
| BCN2679 | Gymnemic acid I |
| 1. Gymnemic acids have been reported to effect a natural treatment for diabetes. 2. Gymnemic acids inhibit rabbit glyceraldehyde-3-phosphate dehydrogenase and induce a smearing of its electrophoretic band and dephosphorylation. | |
| BCN2682 | Humulone |
| 1. Humulone has antioxidant activity. 2. Humulone is an antispasmodic agent. 3. Humulone has antiviral and antibacterial activities. 4. Humulone, a bone resorption inhibitor, induces apoptosis may via its antioxidative activity in the premyocytic leukemia cell line HL-60 between 1 and 100 micrograms/ml. 5. Humulone is a potent angiogenic inhibitor, can inhibit cyclooxygenase-2 and may be a novel powerful tool for the therapy of various angiogenic diseases involving solid tumor growth and metastasis. | |
