Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 17

  1. Cat.No. Product Name Information/Activity
  2. BCC7750 SGS 518 oxalate 445441-27-0 SGS 518 oxalate chemical structure
  3. BCC6709 Metergoline Metergoline is a psychoactive drug of the ergoline chemical class which acts as a ligand for various serotonin and dopamine receptors. Metergoline chemical structure
  4. BCC5663 2-Methyl-5-hydroxytryptamine hydrochloride 2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects. 2-Methyl-5-hydroxytryptamine hydrochloride chemical structure
  5. BCC1114 Mianserin HCl Mianserin hydrochloride (Org GB 94) is a H1 receptor inverse agonist and is a psychoactive agent of the tetracyclic antidepressant. Mianserin HCl chemical structure
  6. BCC7218 AS 19 AS19 is a potent, selective 5-HT7 receptor agonist with an IC50 value of 0.83 nM and a Ki of 0.6 nM. AS19 is selective for 5-HT7 over 5-HT1A, 5-HT1B, 5-HT1D, and 5-HT5A receptors (Kis = 89.7 nM, 490 nM, 6.6 nM and 98.5 nM, respectively). AS19 enhances memory consolidation and reverses Scopolamine- or Dizocilpine-induced amnesia. AS 19 chemical structure
  7. BCC7517 LP 12 hydrochloride 1185136-22-4 LP 12 hydrochloride chemical structure
  8. BCC7399 LP 44 824958-12-5 LP 44 chemical structure
  9. BCC7990 DR 4485 hydrochloride 402942-53-4 DR 4485 hydrochloride chemical structure
  10. BCC7101 LY 215840 137328-52-0 LY 215840 chemical structure
  11. BCC5937 SB 258719 hydrochloride 1217674-10-6 SB 258719 hydrochloride chemical structure

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