Parkinson's Disease Research

Parkinson's disease (PD) is a degenerative disease of the central nervous system that often impairs motor skills, speech, and other functions. Symptoms of the disease include resting tremor, bradykinesia and rigidity. The primary symptoms are the result of decreased stimulation of the motor cortex by the basal ganglia, normally caused by the insufficient formation and action of dopamine, which is produced in the dopaminergic neurons of the brain. Symptoms of the disease appear once 50-80% of dopamine neurons have died. Parkinson's disease is both chronic and progressive.

Parkinson's Disease Research Products Targets

Products for Parkinson's Disease Research - Page 16

  1. Cat.No. Product Name Information/Activity
  2. BCC7888 EMDT oxalate EMDT oxalate is a selective 5-HT EMDT oxalate chemical structure
  3. BCC7919 ST 1936 oxalate 1210-81-7 ST 1936 oxalate chemical structure
  4. BCC7807 WAY 208466 dihydrochloride 1207064-61-6 WAY 208466 dihydrochloride chemical structure
  5. BCC7650 BGC 20-761 High affinity 5-HT<sub>6</sub> antagonist BGC 20-761 chemical structure
  6. BCC6127 MS 245 oxalate 275363-58-1 MS 245 oxalate chemical structure
  7. BCC7629 NPS ALX Compound 4a dihydrochloride NPS ALX Compound 4a is a potent and selective 5-hydroxytryptamine6 (5-HT6) receptor antagonist with an IC50 of 7.2 nM, which also has a great binding affinity with Ki of 0.2 nM. NPS ALX Compound 4a dihydrochloride chemical structure
  8. BCC7512 Ro 04-6790 202466-68-0 Ro 04-6790 chemical structure
  9. BCC7216 SB 258585 hydrochloride 1216468-02-8 SB 258585 hydrochloride chemical structure
  10. BCC1924 SB 271046 hydrochloride SB271046 Hydrochloride is a potent, selective and orally active 5-HT6 receptor antagonist with pKi of 8.9. SB 271046 hydrochloride chemical structure

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