Epilepsy Research

Epilepsy is a group of neurological conditions consisting of recurrent, usually unprovoked epileptic seizures. Epileptic seizures have recently been defined as "a transient occurrence of signs and/or symptoms due to abnormal, excessive or synchronous neuronal activity in the brain". Epilepsy is one of the most common disorders of the brain, with one in 10 people suffering at least one seizure in their lifetime. There are over 40 different types of epilepsy, each of which presents with its own unique combination of seizure type, typical age of onset, EEG findings, treatment, and prognosis.

Epilepsy Research Products Targets

Products for Epilepsy Research - Page 53

  1. Cat.No. Product Name Information/Activity
  2. BCC7709 Margatoxin Margatoxin, an alpha-KTx scorpion toxin, is a high affinity inhibitor of Kv1.3 (Kd=11.7 pM). Margatoxin inhibits the Kv1.2 (Kd=6.4 pM) and Kv1.1 (Kd=4.2 nM). Margatoxin, a 39 amino-acid-long peptide, is isolated from the venom of the scorpion Centruroides margaritatus and widely used in ion channel research. Margatoxin chemical structure
  3. BCC7927 Psora 4 Potent K<sub>V</sub>1.3 channel blocker Psora 4 chemical structure
  4. BCC6044 RuBi-4AP 851956-02-0 RuBi-4AP chemical structure
  5. BCC5990 ShK-Dap22 220384-25-8 ShK-Dap22 chemical structure
  6. BCC7554 Tetraethylammonium chloride Non-selective K<sup>+</sup> channel blocker Tetraethylammonium chloride chemical structure
  7. BCC7784 UK 78282 hydrochloride 136647-02-4 UK 78282 hydrochloride chemical structure
  8. BCC7232 XE 991 dihydrochloride XE 991 dihydrochloride, a Kv7 (KCNQ) channels blocker, potently inhibits Kv7.1 (KCNQ1), Kv7.2 (KCNQ2), Kv7.2 + Kv7.3 (KCNQ3) channel, and M-current with IC50s of 0.75 µM, 0.71 µM, 0.6 μM, and 0.98 µM, respectively. XE 991 dihydrochloride chemical structure
  9. BCC4907 Fluticasone propionate Fluticasone propionate is a high affinity, selective GR (glucocorticoid receptor) agonist which is derived from fluticasone used to treat asthma and allergic rhinitis. Fluticasone propionate chemical structure
  10. BCC6351 GMQ hydrochloride 5361-15-9 GMQ hydrochloride chemical structure
  11. BCC6054 Neuropeptide SF (mouse, rat) 230960-31-3 Neuropeptide SF (mouse, rat) chemical structure

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