Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 19

  1. Cat.No. Product Name Information/Activity
  2. BCC6893 CGP 20712 dihydrochloride 1216905-73-5 CGP 20712 dihydrochloride chemical structure
  3. BCC4330 Metoprolol Tartrate Metoprolol is a cardioselective β1-adrenergic blocking agent. Metoprolol Tartrate chemical structure
  4. BCC4340 Timolol Maleate (S)-Timolol Maleate (L-714,465 Maleate) is a non-cardioselective hydrophilic β-adrenoceptor blocker. (S)-Timolol Maleate is widely used as standard medication for intraocular pressure (glaucoma) by preventing the production of aqueous humor. (S)-Timolol Maleate can be used for hypertension, angina pectoris and myocardial infarction. Timolol Maleate chemical structure
  5. BCC4349 Formoterol Hemifumarate Formoterol fumarate(Foradil) is a potent, selective and long-acting β2-adrenoceptor agonist. Formoterol Hemifumarate chemical structure
  6. BCC6937 Procaterol hydrochloride 62929-91-3 Procaterol hydrochloride chemical structure
  7. BCC4338 Salbutamol Sulfate Salbutamol Sulfate is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 µM. Salbutamol Sulfate chemical structure
  8. BCC1920 Salmeterol xinafoate Salmeterol xinafoate is a long-acting beta-2 adrenergic receptor (β2AR) agonist, with Ki of 1.5 nM for WT β2AR, and used for asthma treatment. Salmeterol xinafoate chemical structure
  9. BCC6911 Zinterol hydrochloride Zinterol (MJ 9184) is a potent and selective β2-adrenoceptor agonist. Zinterol increases ICa in a concentration-dependent manner with an EC50 of 2.2 nM. Zinterol hydrochloride chemical structure
  10. BCC4029 ICI 118,551 hydrochloride ICI 118,551 (hydrochloride) is a highly selective β2 adrenergic receptor antagonist, with Kis of 0.7, 49.5 and 611 nM for β2, β1 and β3 receptors, respectively. ICI 118,551 hydrochloride chemical structure
  11. BCC6860 BRL 37344, sodium salt BRL 37344 sodium (BRL 37344A) is a specific β3-adrenergic receptor agonist. BRL 37344 sodium treatment significantly lowers the body weight of obese mice. BRL 37344, sodium salt chemical structure

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