Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 17

  1. Cat.No. Product Name Information/Activity
  2. BCC6851 ARC 239 dihydrochloride 55974-42-0 ARC 239 dihydrochloride chemical structure
  3. BCC7521 Atipamezole hydrochloride Atipamezole hydrochloride is a synthetic α2-adrenoceptor antagonist with a Ki of 1.6 nM. Atipamezole hydrochloride chemical structure
  4. BCC6948 BRL 44408 maleate 681806-46-2 BRL 44408 maleate chemical structure
  5. BCC6797 Efaroxan hydrochloride 89197-00-2 Efaroxan hydrochloride chemical structure
  6. BCC6798 Idazoxan hydrochloride Idazoxan hydrochloride (RX 781094 hydrochloride) is an α2-adrenoceptor antagonist and is also a imidazoline receptors (IRs) antagonist competitively antagonized the centrally induced hypotensive effect of imidazoline-like drugs (IMs). Idazoxan hydrochloride also improves motor symptoms in Parkinson’s disease, L-DOPA-induced dyskinesias, and experimental Parkinsonism. Idazoxan hydrochloride chemical structure
  7. BCC6875 Imiloxan hydrochloride 81167-22-8 Imiloxan hydrochloride chemical structure
  8. BCC7449 JP 1302 dihydrochloride JP1302 dihydrochloride is a selective, high affinity antagonist of the alpha2C-adrenoceptor (α2C-adrenoceptor), with a Kb value (antagonist activity) of 16 nM and a Ki (binding affinity) value of 28 nM. JP 1302 dihydrochloride chemical structure
  9. BCC4923 Mirtazapine Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors. Mirtazapine chemical structure
  10. BCC6834 Rauwolscine hydrochloride Rauwolscine hydrochloride is a potent and specific α2 adrenergic receptor antagonist with a Ki of 12 nM. Rauwolscine hydrochloride chemical structure
  11. BCC6876 RS 79948 hydrochloride 186002-54-0 RS 79948 hydrochloride chemical structure

Items 161 to 170 of 631 total