Depression Research

Major depressive disorder, often referred to as major depression, is a heterogenous condition with complex and diverse neurobiological etiologies. Depression is characterized by a triad of symptoms: low or depressed mood, anhedonia and low energy or fatigue. Approximately 15% of the population in developed countries has been affected by depression in their lifetime and the chance of developing depression is twice as high in women. 40-50% of depressive causes are inheritable (genes as yet unidentified) and the remaining 50-60% of causes are caused by environmental stressors.

Depression Research Products Targets

Products for Depression Research - Page 16

  1. Cat.No. Product Name Information/Activity
  2. BCC4327 Guanabenz Acetate Guanabenz (Acetate) (BR-750) is an alpha-2 selective adrenergic agonist used as an antihypertensive agent. Guanabenz Acetate chemical structure
  3. BCC1609 Guanfacine hydrochloride Guanfacine hydrochloride, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors. Guanfacine hydrochloride chemical structure
  4. BCC4351 Medetomidine HCl Medetomidine hydrochloride is an agonist of adrenergic alpha-2 receptor, which is used in veterinary medicine for its analgesic and sedative properties. Medetomidine HCl chemical structure
  5. BCC5163 Moxonidine hydrochloride Moxonidine Hydrochloride is a selective agonist at the imidazoline receptor subtype 1, used as antihypertensive agent. Moxonidine hydrochloride chemical structure
  6. BCC6086 RWJ 52353 245744-10-9 RWJ 52353 chemical structure
  7. BCC7436 ST 91 4749-61-5 ST 91 chemical structure
  8. BCC7991 TC-G 1000 245744-18-7 TC-G 1000 chemical structure
  9. BCC4357 Tizanidine HCl Tizanidine hydrochloride is an α2-adrenergic receptor agonist and inhibits neurotransmitter release from CNS noradrenergic neurons. Tizanidine HCl chemical structure
  10. BCC5226 UK 14,304 Brimonidine (UK 14304) is a full α2-adrenergic receptor (α2-AR) agonist. UK 14,304 chemical structure
  11. BCC7336 A 80426 mesylate 152148-64-6 A 80426 mesylate chemical structure

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