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Trollisin I

CAS# 911063-04-2

Trollisin I

2D Structure

Catalog No. BCX2191----Order now to get a substantial discount!

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Trollisin I: 5mg $200 In Stock
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Trollisin I

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Chemical Properties of Trollisin I

Cas No. 911063-04-2 SDF File under preparation.
PubChem ID N/A Appearance Powder
Formula C27H30O12 M.Wt 546.5
Type of Compound Alkaloids Storage Desiccate at -20°C
Solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
General tips For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20℃ for several months.
We recommend that you prepare and use the solution on the same day. However, if the test schedule requires, the stock solutions can be prepared in advance, and the stock solution must be sealed and stored below -20℃. In general, the stock solution can be kept for several months.
Before use, we recommend that you leave the vial at room temperature for at least an hour before opening it.
About Packaging 1. The packaging of the product may be reversed during transportation, cause the high purity compounds to adhere to the neck or cap of the vial.Take the vail out of its packaging and shake gently until the compounds fall to the bottom of the vial.
2. For liquid products, please centrifuge at 500xg to gather the liquid to the bottom of the vial.
3. Try to avoid loss or contamination during the experiment.
Shipping Condition Packaging according to customer requirements(5mg, 10mg, 20mg and more). Ship via FedEx, DHL, UPS, EMS or other couriers with RT, or blue ice upon request.

Source of Trollisin I

The herbs of Polygonum orientale Linn.

Trollisin I Dilution Calculator

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Trollisin I Molarity Calculator

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Preparing Stock Solutions of Trollisin I

1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.8298 mL 9.1491 mL 18.2983 mL 36.5965 mL 45.7457 mL
5 mM 0.366 mL 1.8298 mL 3.6597 mL 7.3193 mL 9.1491 mL
10 mM 0.183 mL 0.9149 mL 1.8298 mL 3.6597 mL 4.5746 mL
50 mM 0.0366 mL 0.183 mL 0.366 mL 0.7319 mL 0.9149 mL
100 mM 0.0183 mL 0.0915 mL 0.183 mL 0.366 mL 0.4575 mL
* Note: If you are in the process of experiment, it's necessary to make the dilution ratios of the samples. The dilution data above is only for reference. Normally, it's can get a better solubility within lower of Concentrations.

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References on Trollisin I

Qualitative and Quantitative Analysis of 24 Components in Jinlianhua Decoction by UPLC-MS/MS.[Pubmed:32214429]

Chromatographia. 2019;82(12):1801-1825.

Jinlianhua Decoction (JD), composed of Flos Trollii, Herba Taraxaci, Folium Isatidis, Radix Puerariae Lobatae, and Folium Perillae in a ratio of 6:15:10:10:6, is a prescription for Fengwen which is a group of febrile diseases due to wind in Chinese medicine. It was originally used for the prevention and treatment of severe acute respiratory syndrome (SARS), and could also be used to treat influenza due to their common pathomechanism. To elucidate the unclear pharmacodynamic basis of JD, the LC-QExactive-MS system was used to qualitatively analyze its main components in this study. As a result, 89 compounds were identified and 24 important ones were selected thereby to further perform the simultaneous quantification in 8 batches of JD samples using LC-QTrap-MS with multiple reaction monitoring (MRM). Based on the qualitative and quantitative results in combination with the bioactivities reported, 16 compounds including orientin, 2''-O-beta-l-galactopyranosylorientin, puerarin, Trollisin I, rosmarinic acid, 2''-O-(2'''-methylbutanoyl) isoswertisin, daidzin, scutellarin, 3'-methoxy puerarin, vitexin, 3'-hydroxy puerarin, 2''-O-(2'''-methylbutanoyl) vitexin, kaempferol, caffeic acid, 3,4-dimethoxybenzoic acid, and cynaroside were determined as the major components of JD. This study provides a useful combinational method for analyzing the major pharmacodynamic substances of JD and lays a foundation for the quality control research of the decoction.

Three new acylated flavone C-glycosides from the flowers of Trollius chinensis.[Pubmed:19504385]

J Asian Nat Prod Res. 2009;11(5):426-32.

Three new flavone C-glycosides with the substitution of the unusual acyl, 2''-O-veratroylisoswertisin (1), 3''-O-2-methylbutyrylisoswertiajaponin (2), and 3''-O-2-methylbutyrylvitexin (3), together with the known compounds of 2''-O-2-methylbutyrylisoswertisin (4), 3''-O-2-methylbutyrylisoswertisin (5), and Trollisin I (6) were isolated from the antibacterial fraction of the aqueous extract of the flowers of Trollius chinensis. The structural elucidations of these compounds were carried out by a detailed analysis of the NMR and MS spectra.

Antiviral flavonoid-type C-glycosides from the flowers of Trollius chinensis.[Pubmed:17193271]

Chem Biodivers. 2006 Mar;3(3):343-8.

Two new flavonoid-type C-glycosides, Trollisin I (= (1S)-1,5-anhydro-1-[2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxy-4-oxo-4H-[1]benzopyran-8-yl]-2-O-(2-methylbutanoyl)-D-glucitol; 1) and its 2-O-benzoyl congener Trollisin II (2), were isolated from Trollius chinensis Bunge, together with the two known compounds 2''-O-(2'''-methylbutanoyl)isoswertisin (3) and vitexin galactoside (4). All compounds were identified by HR-ESI-MS and in-depth NMR-spectroscopic analyses. In antiviral assays, compound 3 was found to be moderately active towards influenza virus A.

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